Klinik für Kardiologie, Pneumologie und Innere Medizin

Treatments according to OPS

Service Number of cases OPS key Info
Examination of the left side of the heart with a tube (catheter) inserted into the heart via an artery 459 1-275.0
Ultrasound of the heart (echocardiography) through the oesophagus - TEE 412 3-052
Computed tomography of the chest with contrast medium 302 3-222
Measurement of lung function in an airtight cabin - whole body plethysmography 261 1-710
Insertion of a small tube (cannula) or catheter into the space between the lungs and ribs for the drainage of fluid 247 8-144.1
Treatment of cardiac arrhythmias with electric shocks - defibrillation 234 8-640.0
Radio-controlled cardiological telemetry 223 8-933
Computed tomography (CT) of the head without contrast medium 198 3-200
Use of a face, nasal, or laryngeal mask for mechanical ventilation 171 8-706
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels 138 8-837.m0
Examination of the trachea and the bronchi by endoscopy 131 1-620.00
Patient education 121 9-500.0
Examination of the trachea and the bronchi by endoscopy 117 1-620.01
Additional information on materials used 117 8-83b.07
Computed tomography (CT) of the chest without contrast medium 109 3-202
Computed tomography of the abdomen with contrast medium 99 3-225
Procedure for dialysing the blood outside the body with removal of the poison over a concentration gradient - dialysis 89 8-854.2
Investigation of the activity of the heart and lungs during sleep 80 1-791
Injection or administration of medicines into the urinary bladder 78 8-132.x
Transfusion of blood, red blood cells or platelets from a donor to a recipient 77 8-800.c0
Insertion of a tube into the trachea for ventilation - intubation 68 8-701
Computed tomography of the head with contrast medium 62 3-220
Measurement of the electrical activity of the heart without a tube (catheter) inserted into the heart via an artery 59 1-266.0
Insertion or exchange of a tube (catheter) in a large vein 57 8-831.0
Examination of the bronchi by taking a sample of fluid or tissue with a needle 45 1-843
Magnetic resonance imaging (MRI) of the heart with contrast medium 40 3-824.0
Magnetic resonance imaging (MRI) of the head without contrast medium 38 3-800
Insertion of a small tube (cannula) or catheter into the space between the lungs and ribs for the drainage of fluid 36 8-144.0
Insertion of a cardiac pacemaker or of a defibrillator 34 5-377.30
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels 34 8-837.00
Insertion of a small tube (cannula) or catheter into the space between the lungs and ribs for the drainage of fluid 33 8-144.2
Cardiac or cardiopulmonary resuscitation 33 8-771
Magnetic resonance imaging (MRI) of the head with contrast medium 32 3-820
Treatment by the targeted insertion of a needle into the chest with subsequent administration or removal of substances, e.g. fluid 29 8-152.1
Function-orientated physical exercises and uses 29 8-561.1
Examination of the trachea and the bronchi by endoscopy 28 1-620.0x
Additional information on materials used 28 8-83b.03
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels 27 8-837.m1
Computed tomography (CT) of the abdomen without contrast medium 26 3-207
Examination of the space between the lungs and ribs by taking a sample of fluid or tissue with a needle 22 1-844
Removal, exchange or correction of a pacemaker or defibrillator 22 5-378.52
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 21 1-430.10
(Neuro-)psychological assessment or establishing the psychosocial background such as financial, occupational and family situation 19 1-901.0
Ultrasound of the lungs with access through the respiratory tract 19 3-05f
Magnetic resonance imaging (MRI) of the heart without contrast medium 19 3-803.0
Other operations on blood vessels 19 5-399.5
Additional information on materials used 18 8-83b.0c
Examination of nerve conduction - ENG 17 1-206
Taking a tissue sample (biopsy) of the respiratory tract through the skin, guided by imaging procedures such as ultrasound 17 1-432.01
Taking a tissue sample (biopsy) of the respiratory tract through the skin, guided by imaging procedures such as ultrasound 17 1-432.0x
Measurement of the composition of respired air at rest and on physical exercise 16 1-712
Radiotherapy with high-energy beams for cancer - high voltage radiotherapy 16 8-522.d0
Computed tomography (CT) of the neck without contrast medium 15 3-201
Removal, exchange or correction of a pacemaker or defibrillator 15 5-378.51
Insertion of a temporary, artificial tracheal opening 14 5-311.1
Anaesthesia with administration of an anaesthetic into a vein 14 8-900
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 13 1-430.1x
Use of a cardiac pacemaker that can be used in a magnetic resonance tomography unit 13 5-934.0
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 12 1-430.20
Insertion of a cardiac pacemaker or of a defibrillator 12 5-377.1
Other operations on the intestine 12 5-469.d3
Computed tomography of the neck with contrast medium 11 3-221
Insertion or exchange of a tube (catheter) in a large vein 11 8-831.5
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 10 1-430.2x
Taking a tissue sample (biopsy) of other organs or tissues through the skin, guided by imaging procedures such as ultrasound 10 1-494.2
Computed tomography (CT) of the pelvis without contrast medium 10 3-206
Injection or administration of medicines into the urinary bladder 10 8-132.2
Computed tomography (CT) of the spine and the spinal cord without contrast medium 9 3-203
Magnetic resonance imaging (MRI) of the abdominal cavity with contrast medium 9 3-825
Computer-assisted analysis of the images with 3D-analysis 9 3-990
Injection or administration of medicines into the urinary bladder 9 8-132.3
Installation and adjustment of a mechanical ventilator for home use 9 8-716.00
Transfusion of blood, red blood cells or platelets from a donor to a recipient 9 8-800.c1
Taking a tissue sample (biopsy) of lymph nodes, spleen or thymus gland through the skin, guided by imaging procedures such as ultrasound 8 1-426.3
Injection or administration of medicines into the urinary bladder 8 8-132.0
Exchange or removal of a urinary catheter through the abdominal wall 8 8-133.0
Intensive care monitoring of respiration, the heart and the circulation with measurement of the pressure in the superior vena cava (central venous pressure) 8 8-931.0
8 8-981.21
Taking a tissue sample (biopsy) of the respiratory tract with a needle through the skin 7 1-431.0
Taking a tissue sample (biopsy) of the respiratory tract through the skin, guided by imaging procedures such as ultrasound 7 1-432.00
Computed tomography (CT) of the musculoskeletal system without contrast medium 7 3-205
X-rays of the arteries in the legs with contrast medium 7 3-607
Imaging procedure to show the heart by means of radioactivity and computed tomography (SPECT) 7 3-721.00
Magnetic resonance imaging (MRI) of the neck without contrast medium 7 3-801
Surgical removal or destruction of diseased tissue in the large intestine 7 5-452.61
7 5-896.1d
Installation and adjustment of a mechanical ventilator for home use 7 8-716.10
Additional information on materials used 7 8-83b.06
Treatment procedure to maintain and encourage practical everyday and social skills - psychosocial intervention 7 9-401.22
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 6 1-430.x
Computed tomography of the heart with contrast medium 6 3-224.0
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels 6 8-837.m3
Measurement of the brain waves - EEG 5 1-207.0
Removal, exchange or correction of a pacemaker or defibrillator 5 5-378.07
Simple surgical closure of the skin or the subcutaneous tissues after injuries, e.g. with a suture 5 5-900.04
Intestinal lavage 5 8-121
Insertion of a small tube (cannula) or catheter in the kidney or urinary tract for the drainage of fluid other than urine 5 8-147.x
Treatment by extreme cooling (hypothermia) to reduce the need for oxygen 5 8-607.0
Transfusion of other plasma components or genetically engineered blood proteins 5 8-812.53
Blood purification outside the body through a combination of haemofiltration and dialysis 5 8-855.81
Monitoring of the brain waves for more than 24 hours 5 8-920
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy 4 1-430.30
X-rays of the kidney and urinary tract with contrast medium 4 3-13d.5
Computed tomography (CT) of the blood vessels other than the main arteries and veins near the heart with contrast medium 4 3-228
Magnetic resonance imaging (MRI) of the neck with contrast medium 4 3-821
Magnetic resonance imaging (MRI) of the spine and spinal cord with contrast medium 4 3-823
Treatment by injecting a medicine into an organ or tissue, or removal of excess fluid (effusion) e.g. from the joints 4 8-020.8
Radiotherapy with high-energy beams for cancer - high voltage radiotherapy 4 8-522.90
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels 4 8-837.k0
Measurement of the electrical activity of the muscles - EMG not specified 1-205
Measurement of brain waves triggered by targeted stimuli (evoked potentials) not specified 1-208.2
Measurement of brain waves triggered by targeted stimuli (evoked potentials) not specified 1-208.4
Measurement of the electrical activity of the heart with a tube (catheter) inserted into the heart via an artery - electrophysiological investigation not specified 1-265.1
Measurement of the electrical activity of the heart with a tube (catheter) inserted into the heart via an artery - electrophysiological investigation not specified 1-265.f
Measurement of the electrical activity of the heart without a tube (catheter) inserted into the heart via an artery not specified 1-266.1
Examination of the right side of the heart with a tube (catheter) inserted into the heart via a vein not specified 1-273.x
Examination of the left side of the heart with a tube (catheter) inserted into the heart via an artery not specified 1-275.1
Taking a tissue sample (biopsy) of the bone marrow without surgical incision not specified 1-424
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy not specified 1-430.00
Taking a tissue sample (biopsy) of the respiratory tract by endoscopy not specified 1-430.0x
Taking a tissue sample (biopsy) of the respiratory tract with a needle through the skin not specified 1-431.1
Taking a tissue sample (biopsy) of the respiratory tract through the skin, guided by imaging procedures such as ultrasound not specified 1-432.02
Taking a tissue sample (biopsy) of the respiratory tract through the skin, guided by imaging procedures such as ultrasound not specified 1-432.1
Analysis of the amount of carbon monoxide taken in and given off by the lungs not specified 1-711
Standard screening examination of elderly people not specified 1-771
Investigation of the of the brain, heart, and muscle activity, and respiration during sleep not specified 1-790
Extensive investigation of hormone function not specified 1-797.0
Examination of the abdominal cavity by taking a sample of fluid or tissue with a needle not specified 1-853.2
Examination of a joint or of a bursa by taking a sample of fluid or tissue with a needle not specified 1-854.1
Examination of a joint or of a bursa by taking a sample of fluid or tissue with a needle not specified 1-854.7
Other examination by taking a sample of fluid or tissue with a needle not specified 1-859.x
Comprehensive ultrasound examination with contrast medium for investigating and excluding suspected diagnoses not specified 3-030
Comprehensive ultrasound examination of the heart (echocardiography) by attaching the ultrasound transponder to the chest wall (transthoracic) during physical exercise not specified 3-031
X-rays of the bronchi with contrast medium not specified 3-135
X-rays of the kidney and urinary tract with contrast medium not specified 3-13d.6
X-rays of the urinary bladder with contrast medium not specified 3-13f
Computed tomography (CT) of the heart without contrast medium not specified 3-204
Computed tomography (CT) of the blood vessels without contrast medium not specified 3-208
Other computed tomography (CT) without contrast medium not specified 3-20x
Computed tomography (CT) of the spine and the spinal cord with contrast medium not specified 3-223
Computed tomography of the heart with contrast medium not specified 3-224.30
Other computed tomography (CT) with contrast medium not specified 3-22x
X-rays of the arteries in the pelvis with contrast medium not specified 3-605
Imaging procedure to show the thyroid gland by means of radioactivity (scintigraphy) not specified 3-701
Imaging procedure to show the musculoskeletal system using nuclear radiation (scintigraphy) not specified 3-705.0
Imaging procedure to show the heart by means of radioactivity and computed tomography (SPECT) not specified 3-721.01
Imaging procedure to show the heart by means of radioactivity and computed tomography (SPECT) not specified 3-721.10
Imaging procedure to show the heart by means of radioactivity and computed tomography (SPECT) not specified 3-721.20
Imaging procedure to show the heart by means of radioactivity and computed tomography (SPECT) not specified 3-721.21
Imaging procedure to demonstrate the heart using nuclear radiation and computed tomography (SPECT/CT) not specified 3-731
Imaging procedure to demonstrate the lung using nuclear radiation and computed tomography (SPECT/CT) not specified 3-732.x
Imaging procedure to demonstrate bone using nuclear radiation and computed tomography (SPECT/CT) not specified 3-733.0
Visualisation of the metabolic processes in the whole body with radioactive labelled substances and computed tomography (PET/CT) not specified 3-753.1
Magnetic resonance imaging (MRI) of the spine and spinal cord without contrast medium not specified 3-802
Magnetic resonance imaging (MRI) of the heart without contrast medium not specified 3-803.2
Magnetic resonance imaging (MRI) of the abdominal cavity without contrast medium not specified 3-804
Magnetic resonance imaging (MRI) of the pelvis without contrast medium not specified 3-805
Magnetic resonance imaging (MRI) of the musculoskeletal system without contrast medium not specified 3-806
Magnetic resonance imaging (MRI) of the chest with contrast medium not specified 3-822
Magnetic resonance imaging (MRI) of the heart with contrast medium not specified 3-824.1
Magnetic resonance imaging (MRI) of the heart with contrast medium not specified 3-824.2
Magnetic resonance imaging (MRI) of the blood vessels apart from the main arteries and veins near the heart with contrast medium not specified 3-828
Magnetic resonance imaging (MRI) of the pelvis with contrast medium not specified 3-82a
Magnetic resonance imaging (MRI) of the biliary tract and pancreatic ducts with contrast medium not specified 3-843.0
Quantitative analysis of specific values such as organ function or blood flow rate not specified 3-993
Image fusion from different imaging sources on a computer not specified 3-997
Operation to divide adhesions around a nerve or to relieve pressure on the nerve or to abolish the nerve function not specified 5-056.3
Insertion of a temporary, artificial tracheal opening not specified 5-311.0
Insertion of a temporary, artificial tracheal opening not specified 5-311.2
Surgical removal or destruction of diseased tissue in a bronchus not specified 5-320.0
Other operations on the lungs or bronchi not specified 5-339.70
Obliteration of the space between the lungs and ribs - pleurodesis not specified 5-345.6
Insertion of a cardiac pacemaker or of a defibrillator not specified 5-377.2
Insertion of a cardiac pacemaker or of a defibrillator not specified 5-377.50
Insertion of a cardiac pacemaker or of a defibrillator not specified 5-377.8
Removal, exchange or correction of a pacemaker or defibrillator not specified 5-378.32
Removal, exchange or correction of a pacemaker or defibrillator not specified 5-378.5f
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.11
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.12
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.20
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.24
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.52
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.53
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.56
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.70
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.71
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.72
Surgical opening of the blood vessels or removal of a blood clot not specified 5-380.a2
Surgical removal of a blood clot including the adjacent inner wall of an artery not specified 5-381.70
Surgical removal of part of the aorta with the interposition of a graft not specified 5-384.31
Surgical removal of part of the aorta with the interposition of a graft not specified 5-384.x2
Other surgical removal of blood vessels because of vascular disease or for grafting not specified 5-386.a2
Creating a connection (shunt) between an artery and a vein not specified 5-392.10
Creating another connection between blood vessels (shunt) or inserting a bypass graft not specified 5-393.54
Creating another connection between blood vessels (shunt) or inserting a bypass graft not specified 5-393.55
Surgical closure of a hole in the blood vessel wall with a skin or synthetic flap not specified 5-395.24
Other operations on blood vessels not specified 5-399.6
Other operations on blood vessels not specified 5-399.7
Surgical removal of the spleen not specified 5-413.12
Other operations on the oesophagus not specified 5-429.8
Other operations on the oesophagus not specified 5-429.a
Other operations on the oesophagus not specified 5-429.e
Surgical insertion of a tube into the stomach through the abdominal wall for artificial feeding not specified 5-431.20
Surgical insertion of a tube into the stomach through the abdominal wall for artificial feeding not specified 5-431.2x
Surgical removal or destruction of diseased tissue in the stomach not specified 5-433.52
Other operations on the stomach not specified 5-449.d3
Other operations on the stomach not specified 5-449.t3
Surgical incision into the intestine not specified 5-450.3
Surgical removal or destruction of diseased tissue in the small intestine not specified 5-451.73
Surgical removal or destruction of diseased tissue in the small intestine not specified 5-451.92
Surgical removal or destruction of diseased tissue in the large intestine not specified 5-452.62
Surgical removal or destruction of diseased tissue in the large intestine not specified 5-452.82
Surgical removal of the small intestine not specified 5-454.42
Other operations on the intestine not specified 5-469.e3
Other operations on the intestine not specified 5-469.s3
Other operations on the intestine not specified 5-469.u3
Other abdominal operations not specified 5-549.5
Surgical incision into a kidney, insertion of a tube to drain urine from the kidney, removal of a stone (calculus) through a surgical incision, dilatation of the renal pelvis or removal of a stone by endoscopy not specified 5-550.1
Removal of stones, foreign bodies or collections of blood from the bladder by endoscopy not specified 5-570.4
Surgical creation of a connection between the urinary bladder and skin of the abdomen for artificial urinary drainage not specified 5-572.1
Reduction of a fracture or a separated growth cartilage (epiphyseal cartilage) and external fixation of the bone fragments using devices such as screws or plates not specified 5-790.51
Division of muscles, tendons or their connective tissue sheaths not specified 5-851.99
Surgical amputation of part of the foot or the whole foot not specified 5-865.7
New surgical expert assessment and treatment of a region from which part of the body has been surgically amputated not specified 5-866.4
Other surgical incision into the skin or subcutaneous tissues not specified 5-892.0e
Other surgical incision into the skin or subcutaneous tissues not specified 5-892.17
Other surgical incision into the skin or subcutaneous tissues not specified 5-892.1e
not specified 5-896.1a
not specified 5-896.1e
not specified 5-896.1f
Other surgical removal of the skin or subcutaneous tissues not specified 5-899
Simple surgical closure of the skin or the subcutaneous tissues after injuries, e.g. with a suture not specified 5-900.0e
Nature of the graft material not specified 5-930.4
Use of a cardiac pacemaker that can be used in a magnetic resonance tomography unit not specified 5-934.2
Operation using lasers not specified 5-985.0
Premature termination of an operation (operation not carried out completely) not specified 5-995
Administration of medicines in accordance with List 2 of the procedures list not specified 6-002.p4
Administration of medicines in accordance with List 2 of the procedures list not specified 6-002.p5
Administration of medicines in accordance with List 2 of the procedures list not specified 6-002.p8
Administration of medicines in accordance with List 2 of the procedures list not specified 6-002.pc
Administration of medicines in accordance with List 2 of the procedures list not specified 6-002.r4
not specified 6-006.21
not specified 6-006.23
not specified 6-007.61
Artificial feeding through a vein as the main medical treatment not specified 8-016
Treatment by injecting a medicine into an organ or tissue, or removal of excess fluid (effusion) e.g. from the joints not specified 8-020.x
Removal of a foreign body by endoscopy not specified 8-100.4x
Exchange or removal of a feeding tube inserted into the stomach through the skin not specified 8-123.1
Injection or administration of medicines into the urinary bladder not specified 8-132.1
Insertion, exchange or removal of a ureteral stent not specified 8-137.00
Insertion, exchange or removal of a ureteral stent not specified 8-137.10
Other procedure on the kidney, ureter, bladder or urethra not specified 8-139.00
Insertion of a small tube (cannula) or catheter into another organ or tissue for the drainage of fluid not specified 8-148.0
Treatment by the targeted insertion of a needle into the chest with subsequent administration or removal of substances, e.g. fluid not specified 8-152.0
Treatment by the targeted insertion of a needle into a joint with subsequent administration or removal of substances, e.g. fluid not specified 8-158.h
Treatment by lavage of the lung or the cavity between the lung and ribs not specified 8-173.0
Treatment by lavage of the lung or the cavity between the lung and ribs not specified 8-173.10
Other treatment by irrigation or lavage not specified 8-179.0
Other treatment by irrigation or lavage not specified 8-179.x
Radiotherapy with high-energy beams for cancer - high voltage radiotherapy not specified 8-522.60
Others therapeutic procedures to influence the immune system not specified 8-547.30
Early postoperative treatment and early rehabilitation of patients with diseases of the nervous system or who have had neurosurgery not specified 8-552.9
Treatment by extreme cooling (hypothermia) to reduce the need for oxygen not specified 8-607.x
Treatment of cardiac arrhythmias with electric shocks - defibrillation not specified 8-640.1
Temporary stimulation of the heart rhythm by an external cardiac pacemaker not specified 8-641
Installation and adjustment of a mechanical ventilator for home use not specified 8-716.11
Installation and adjustment of a mechanical ventilator for treatment of respiratory disorders during sleep not specified 8-717.1
not specified 8-718.72
not specified 8-718.73
not specified 8-718.74
not specified 8-718.92
not specified 8-718.93
not specified 8-718.95
Transfusion of blood, red blood cells or platelets from a donor to a recipient not specified 8-800.61
Transfusion of blood, red blood cells or platelets from a donor to a recipient not specified 8-800.c2
Transfusion of blood, red blood cells or platelets from a donor to a recipient not specified 8-800.c3
Transfusion of blood, red blood cells or platelets from a donor to a recipient not specified 8-800.g0
Transfusion of blood, red blood cells or platelets from a donor to a recipient not specified 8-800.g1
Transfusion of blood previously taken from a person - autologous blood transfusion not specified 8-803.2
Transfusion of blood plasma or plasma components or genetically engineered blood proteins not specified 8-810.w3
Transfusion of blood plasma or plasma components or genetically engineered blood proteins not specified 8-810.wd
Transfusion of other plasma components or genetically engineered blood proteins not specified 8-812.60
Filtration of antibodies from the blood not specified 8-821.2
Destruction of the heart tissue because of a cardiac arrhythmia not specified 8-835.20
Treatment of a vessel with access via a tube (catheter) not specified 8-836.0c
Treatment of a vessel with access via a tube (catheter) not specified 8-836.0q
Treatment of a vessel with access via a tube (catheter) not specified 8-836.0s
Treatment of a vessel with access via a tube (catheter) not specified 8-836.k8
Treatment of a vessel with access via a tube (catheter) not specified 8-836.m8
Treatment of a vessel with access via a tube (catheter) not specified 8-836.n3
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels not specified 8-837.m2
Treatment of the heart and/or the coronary arteries with access through a tube (catheter) along the blood vessels not specified 8-837.m4
Additional information on materials used not specified 8-83b.1x
Additional information on materials used not specified 8-83b.70
Additional information on materials used not specified 8-83b.ba
Implantation of non-drug eluting tubing (stents) in blood vessels not specified 8-840.0q
Implantation of non-drug eluting tubing (stents) in blood vessels not specified 8-840.1q
Blood purification outside the body through a combination of haemofiltration and dialysis not specified 8-855.71
Blood purification outside the body through a combination of haemofiltration and dialysis not specified 8-855.80
Blood purification outside the body through a combination of haemofiltration and dialysis not specified 8-855.82
Blood purification outside the body through a combination of haemofiltration and dialysis not specified 8-855.83
Blood purification outside the body through a combination of haemofiltration and dialysis not specified 8-855.84
not specified 8-981.20
not specified 8-981.23
Treatment of physically or functionally induced disorders of speech, language, the voice or swallowing not specified 9-320
Patient education not specified 9-500.1
Patient education not specified 9-500.2